Cell death molecules

Molecules in the intrinsic apoptosis pathway.
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updated November 20, 2022

Description

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These are electostatic potential maps for molecules that regulate the intrinsic cell death pathway and a couple of others for fun. All structures were sourced from https://www.rcsb.org/. The 4 character code in the filename is the PDB acension number. The structures were loaded into pymol (https://pymol.org/2/) and converted to electrostatic maps. These were then exported as STL files, loaded into blender to be cleaned up. I printed them on a Creality Ender S1 using default settings. A lot support is needed so you'll have an hour or two of ASMR fun removing it (or tedium depending on your temperament). 

I apologise for errors, omissions and inaccuracies, I'm not a molecular biologist let alone a structural biologist.

 

1GJH

Human BCL2

1SVC

NFKB bound to DNA

2LPC

BCLxL

2M04

BCLxL in complex with PUMA

2N9J

Cytomchrome C

3MQP

BFL-1 in complex with NOXA

4WMS

MCL1

6X8O

BIM

4ZIE

BAX in complex with BIM

 

 

The MCL1 structure seems to be at a different scale to the others. I don't know why that is.

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